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    Houston Astros @ Cleveland Guardians

    HOU
    Houston AstrosAstrosHOU
    9-15, 2-9 Away
    CLE -149
    CLE
    Cleveland GuardiansGuardiansCLE
    13-11, 7-4 Home
    • Gamecast
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    Game Odds
    Odds by

    2026-04-21T22:10ZOpenMLTotalRL
    Houston AstrosAstrosHOU
    (9-15)
    (9-15, 2-9 Away)
    (9-15)
    Ryan Weiss
    (0-2, 6.75)
    o8
    -115
    +123
    o8
    -118
    +1.5
    -168
    Cleveland GuardiansGuardiansCLE
    (13-11)
    (13-11, 7-4 Away)
    (13-11)
    Parker Messick
    (3-0, 1.05)
    -149
    ML
    -149
    u8
    -102
    -1.5
    +139
    See More Odds

    Recent Schedule

    DATEOPPRESULTSPREADTOTAL
    4/20@CLEW9-2+1.57.0
    4/19vsSTLL7-5-1.59.0
    4/18vsSTLL7-5-1.59.0
    4/17vsSTLL9-4+1.59.0
    4/16vsCOLL3-2-1.58.5

    Betting 101

    The Beginner's Guide to BettingReady to enter the world of sports betting? Here's everything you need to know to get started.

    Matchup Predictor

    Houston Astros
    Cleveland Guardians
    36.2
    %
    63.8
    %

    According to ESPN Analytics

    Hitting Props

    Yordan Alvarez
    HOU LF
    Jose Altuve
    HOU LF
    Carlos Correa
    HOU SS
    Steven Kwan
    CLE LF
    Jose Ramirez
    CLE 3B
    Chase DeLauter
    CLE RF
    Yainer Diaz
    HOU C
    Christian Walker
    HOU 1B
    o0.5
    -265
    u0.5
    +195
    o0.5
    -244
    u0.5
    +180
    o0.5
    -249
    u0.5
    +184
    o0.5
    -233
    u0.5
    +172
    o0.5
    -227
    u0.5
    +168
    o0.5
    -201
    u0.5
    +150
    o0.5
    -195
    u0.5
    +145
    o0.5
    -188
    u0.5
    +140
    See More Odds

    More Hitting Props

    Steven Kwan
    CLE LF
    Carlos Correa
    HOU SS
    Jose Altuve
    HOU LF
    Yainer Diaz
    HOU C
    Yordan Alvarez
    HOU LF
    Christian Walker
    HOU 1B
    Isaac Paredes
    HOU 3B
    Jose Ramirez
    CLE 3B
    o0.5
    -132
    u0.5
    -105
    o0.5
    -130
    u0.5
    -106
    o0.5
    -122
    u0.5
    -113
    o0.5
    -113
    u0.5
    -122
    o0.5
    -106
    u0.5
    -130
    o0.5
    +104
    u0.5
    -144
    o0.5
    +106
    u0.5
    -146
    o0.5
    +109
    u0.5
    -150
    See More Odds

    Pitching Props

    Parker Messick
    CLE SP
    Ryan Weiss
    HOU RP
    o5.5
    +112
    u5.5
    -144
    o3.5
    -107
    u3.5
    -119
    See More Odds

    Game Props

    Cleveland Guardians
    13-11
    Houston Astros
    9-15
    o4.5
    +105
    u4.5
    -135
    o3.5
    -120
    u3.5
    -110
    See More Odds

    Injury Report

    Houston Astros
    Name, PosStatus
    Jeremy Pena
    SS
    10-Day IL
    Zach Dezenzo
    LF
    10-Day IL
    Bennett Sousa
    RP
    15-Day IL
    Tatsuya Imai
    SP
    15-Day IL
    Joey Loperfido
    LF
    10-Day IL
    Cleveland Guardians
    Name, PosStatus
    Carlos Hernandez
    RP
    OUT
    Andrew Walters
    RP
    15-Day IL
    Gabriel Arias
    SS
    10-Day IL
    Full Injury Report
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